In the group of women with low folate levels a miscarriage was significantly more likely to occur if the fetus had an abnormal chromosome. Id been taking the normal dose of folic acid for months before and during that pregnancy. I did not take any, and had 5 miscarriages. I have learned my lesson - sometimes you need to take charge of your treatment and chase dr's up - not all of them know everything. Since the FDA move, the number of children born with spina bifida in the United States has decreased by one-third, the CDC announced last month. Ju1es sorry for your losses and everything you have been through! I've been finding it hard to get motivated with things after the miscarriage. However, I had a thorough look as I wanted to know for myself and found that 2 of the three mutations I have can cause rec miscarriage and other pregnancy complications. Also, ask questions, youa re entitles to know! What is folic acid and where can I get it? Women with folate deficiencies were 50% more likely to experience early pregnancy losses. The principal storage site of folate is in the liver; it is also actively concentrated in the CSF. The new findings refute a handful of earlier studies linking high folic acid consumption to an increase in miscarriages. Folic acid rapidly appears in the blood, where it is extensively bound to plasma proteins. You should take a 5mg folic acid supplement every day while you are trying to get pregnant, and for at least the first 12 weeks of pregnancy. : Hi--just looking for some advice about supplementing with higher dose of Folic Acid: After a 'TFMR' with neural tube defects in June, my OB has put me on 5mg of Folic Acid, but strongly advised to wait until I have been on higher dose for 3 mths before trying again. If we do not have enough folic acid, the body can make abnormally large red blood cells that do not work properly. Hope I have answered your query. I am now 5 weeks into my pregnancy and have my first prenatal appt. I would ask my dr to explain their thinking behind prescribing aspirin and 5mg of folic - it is always useful to know - I know I want to know why. I received my thrombophilia work up, the gynae said there was no problem, despite the fact that they were positive, as I was only hetero (for 3 different mutations). Not sure about the whole folic acid thing. Folic acid helps make healthy red blood cells, which carry oxygen around the body. 1st time, 3rd time, 4th, 5th, 6th and then after 10 and 1/2 years of patience I had a beautiful baby boy, 100% healthy, no mental or physical problems. This is page 1 of 1 (This thread has 3 messages.). After having my daughter in 2009, I have since had 3 miscarriages and am now 7 weeks pregnant again. She recently gave birth to a baby girl after her Dr did a blood test and discovered that ther was virtually no folic acid in her body leading to problems when the baby`s spinal cord was being formed. It sounds like you have been through it all!A prescription for folic acid is usually given when you have tested positive for the MTHFR mutation in the standard thrombophilia work up. Victoria • Tue, Aug 07 • Rainbow baby due 9th oct 2019. I just had my third miscarriage on Monday at 12 weeks. HelloI'm just going through my 5th mc in two years.After my 3rd mc this time mmc at 11 weeks last September my consultant ran all the blood tests on me and hubby (I had about 8!) A 30-year-old female asked: i take too much folic acid could i probably have a miscarriage? There was a story today in a UK sunday paper about a woman who had a son in 2000 and then had 18 miscarriages. After the 3rd miscarriage we had blood tests done and all came back normal. It is quite a common defect apparently (60% of the pop can have such a mutation) but it can cause problems in pregnancy (which is on its own a hypercoagulative condition= blood clots more in pg). Folic acid, also known as folate, is a vitamin necessary for proper cell growth and embryo development. Has anybody taken this and think its helped have a healthy pregnancy and what is it meant to do?Any advice is appreciated.xx. (5) Unlike folate from food, the process of converting synthetic folic acid to the active form of vitamin … Third time lucky You may have a higher risk if: you have diabetes; you or your partner have a neural tube defect; you have had a previous pregnancy affected by a neural tube defect Please let me know your opinions. After my fourth miscarriage I was prescribed 5mg folic acid which I started taking 3 months before I conceived again. Some foods contain folate naturally. These effects may in part be responsible for the increased risk of miscarriage. Women who get at least 400 micrograms of the vitamin from their diets during the first few weeks of pregnancy can reduce their unborn baby's risk of neural tube defects (NTDs) by as much as 70%. Hey, Have a question about folic acid just wondered if anyone can help. I would also like to add to that, that high dose folic acid increases circulation in the uterus aswell, so that blood flow remains constant from the forming placenta and the hormones being released from the ovaries. No : Low levels associated with neural tube defects and miscarriage. I had 4 consecutive miscarriages in a space of just over 1 year. I am still taking the vitamin D and aspirin, and will do until week 36. Let me know if I can assist you further. Folic acid is a B vitamin that is needed to make health y new cells. Folic acid is a B vitamin found in many supplements and fortified foods. A concern of taking synthetic folic acid is that it may competitively interfere with bioactive folate, since folic acid binds more easily to receptors in your tissue. These birth defects include the paralyzing spinal disease spina bifida, and anencephaly, a fatal disease in which the brain does not develop. The recommended daily intake of folic acid for all women of childbearing age is at least 400 micrograms (mcg), or 0.4 milligrams (mg). Evaluation of the impact of pharmacist polypharmacy reviews within the Govan Social … I've read that if you have a high bmi higher than 30 you should be on a higher dose of folic acid does anyone know if this is true? WebMD does not provide medical advice, diagnosis or treatment. MiL keeps taking money from DH - AIBU to say I never want to go see her again ?! But prenatal vitamins and supplements like folic acid have been shown to reduce the risk of a miscarriage and having a baby that is premature or small for its gestational age. Folic acid is used to treat folic acid deficiency and certain types of anemia. Oct. 15, 2002 -- Taking folic acid before becoming pregnant is one of the best ways to prevent certain birth defects, and now research suggests it may also lower the risk of early miscarriage. Folic Acid or Prenatal Vitamin: I miscarried last Nov 27/13 and I stopped taking my folic acid because I figured I'm not pregnant anymore but just a few weeks ago I realized that I should continue taking the folic acid since my husband and I will be ttc next month. I hope I have helped a bit... Hi ju1es, I am really sorry to hear about your mc's. "Our study did not show any increase in spontaneous abortions at all, in fact it went in the opposite direction," Mills says. Regardless of whether folic acid helps prevent miscarriages, you need to get enough of it to prevent birth defects. Investigational treatments for COVID-19. Many breakfast cereals, rice, pasta, and most breads are now an excellent source of the vitamin, as are beans, leafy green vegetables, and citrus fruits. megaloblastic anaemia or pernicious anaemia caused by folate and/or vitamin B12 I currently take the recommended dose as standard. Should I be taking 400 mcg or 800mcg I was wondering if i took more if it would help our chances since I had a miscarriage (2weeks pregnant) a few weeks ago. Like you, all my tests came back clear for any problems. on 17th june. Folic acid is a vitamin used to prevent or treat a deficiency (lack of) folic acid in the body. folic acid after miscarriage. "This is very encouraging data that suggest we may be reducing the risk of spontaneous abortions in the U.S. by fortifying certain foods," study researcher James L. Mills, MD, an NICHD epidemiologist, tells WebMD. Folic acid/folate and vitamin B12 are both needed in the production of red blood cells and iron utilization. Support for anyone who has had a miscarriage High dose folic acid 5mg for recurrent miscarriage. "One of the easiest ways to do this is to take either a multivitamin or a folic acid or B-vitamin supplement every day if there is any chance at all of becoming pregnant.". Specializes in Family Medicine. 23 JUN 2020 15:13. To use this feature subscribe to Mumsnet Premium - get first access to new features see fewer ads, and support Mumsnet. To comment on this thread you need to create a Mumsnet account. The study, published this week in the Journal of the American Medical Association, was conducted by researchers from Sweden's Karolinka Institute in conjunction with the U.S. National Institute of Child Health and Human Services (NICHD). During this time I was also diagnosed with a vit D deficiency which I was treated for over a week of high dose tablets, and also started low dose aspirin from BFP.I think escape has explained the use of folic acid in women with the MTFHR gene really well. Taking folic acid for at least one month before conception reduces the risk of neural-tube defects, such as spina bifida, by up to 70 percent, according to the Centers for Disease Control and Prevention. Also I'm aware I need to loose weight. During this time I was also diagnosed with a vit D deficiency which I was treated for over a week of high dose tablets, and also started low dose aspirin from BFP. Just wondering if anyone knows how much folic acid is too much? Latest. I just wanted to see if anyone had a successful pregnancy with either folate or 5mg folic acid ? After we eat folate or folic acid, the majority is converted into 5-MTHF before it enters the bloodstream, this metabolic process differs slightly between folate and folic acid. But Katherine Lyon-Daniel of the CDC's folic acid education campaign tells WebMD that it is still difficult for a woman to know if she is getting enough folic acid through diet alone. I had done all the tests from the fertility doctor and he mentioned in little detail that I had mthfr c677t homozygous & told me that this just meant my body had an enzyme that depletes folic acid and I was to increase my dose on top of my prenatal vitamins to 5mg a day. A higher folic acid dose of 15 mg has also been used, but only for up to 60 days. You can consult a gynecologist to look for any possible causes for miscarriage. Third miscarriage was much earlier and I had a natural mc. Folic acid given therapeutically enters the portal circulation largely unchanged, since it is a poor substrate for reduction by dihydrofolate reductases. Oct. 15, 2002 -- Taking folic acid before becoming pregnant is one of the best ways to prevent certain birth defects, and now research suggests it may also lower the risk of early miscarriage. After my fourth miscarriage I was prescribed 5mg folic acid which I started taking 3 months before I conceived again. It is still unbelievable, as I never thought I would have another baby again, but I am confident that the influx of one of the vitamins I increased in my diet helped this baby stick.Hope everything works out for you in the future. Excluded from family because we didn’t go for Xmas lunch, Long term partner’s teenage daughters completely reject me, We’re looking for parents in the North, Midlands or South East to take part in online focus groups, Find out what Mumsnet users thought of Echo by Lloyd’s Pharmacy, Talk widget showing discussions of the day & trending threads, Subscribe to Mumsnet emails direct to your inbox. Top Treatment Tips, The D&C (Dilation and Curettage) Procedure. Folic Acid questions? Folic acid in its natural form is called folate. to prevent recurrence ; also dose recommended for women who are: receiving anti-epileptic medication (1) or ; who have diabetes (2) or; who have sickle cell disease (3) or Folate deficiency also has been associated with placental separation during pregnancy, pregnancy-induced hypertension, and low blood supply to the placenta. Four groups of Wistar rats were classified on the basis of physiological status (virgin v. pregnant) and the experimental diet administered (folic-acid-supplemented, 40 mg/kg diet v. control, 2 mg folic acid/kg diet)(equivalent to 2176 mg for a 120lb woman). Ovulation Tool: Find Your Most Fertile Days. I was put on 5mg folic acid immediately and told to take it for 1-3 months before ttc again (i took it for 2 months before my next bfp). This causes folate deficiency anaemia, which can cause tiredness and other symptoms. In fact Duphaston was given to prevent miscarriage. Folic acid supplements at the time of conception helps to prevent neural tube defects. I'm taking normal vitamins in the morning but s : After my miscarriage (a year ago) I was precribed a 5 milligram folic acid dosage by my obgyn. I got our results back beginning December which came back clear, he advised to take low dose apirin! From December to now we haven't use any contraception I was beginning to think it would never happen when I got a bfp 14/8.I started spotting on and off from 5 weeks - 6 weeks 5 days I had hcg bloods taken and scans which showed only a sac no heartbeat. It’s the synthetic form of folate.Folic acid is used by your body to make new cells and produce DNA. Relatively nontoxic. What foods have folic acid? The finding suggests that a 1998 mandate by the U.S. Food and Drug Administration to fortify grain products with folic acid (the synthetic form of the vitamin) may prevent miscarriage in some women, in addition to lowering their risk for having a child with a class of birth defects known as … Folic acid or folate, which is referred to as the ‘pregnancy superhero’, should be consumed by women before and after they get pregnant. Researchers compared 468 women who had miscarriages between six and 12 weeks of their pregnancies with 921 women who were also in their first trimester, but had not miscarried. If you have a higher risk of having a pregnancy affected by neural tube defects you will be advised to take a higher dose of 5mg folic acid. The researchers concluded that countries that have fortified their food supplies with folic acid and those considering it can trust that fortification most likely will not increase spontaneous abortion rates and might even decrease them. 800 mcg folic acid with or without 800 mg docosahexaenoic acid daily for 6 months. Talk to your doctor about taking folic acid supplements to help you recover from the miscarriage. Women who had high levels of folate in their blood were no more likely to have miscarriages than those who had lower levels. In Sweden, where the grain supply is 5mg folic acid after miscarriage fortified with folic acid is used by body. This causes folate deficiency also has been associated with neural tube defects and all came back.... To fortify certain grain products with folic acid for months before I conceived again turn folic 5mg. Fed on the diets for 3 weeks wanted to see if anyone knows how much folic acid I... 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